【摘要】 目的 :观察口服萍芷片对慢性鼻窦炎鼻息肉组织中炎性细胞浸润情况的影响。方法 :将 80例慢性鼻窦炎鼻息肉患者随机分为 2组 :萍芷片组和对照组 ,每组 4 0例。萍芷片组术前口服萍芷片 ,连服 30d ;对照组术前未作任何治疗。将两组所取得的鼻息肉组织标本分别进行苏木精 伊红染色和免疫组化染色 ,显微镜下观察炎性细胞浸润情况。结果 :萍芷片组鼻息肉组织中CD 11b +、CD7+阳性细胞的浸润数明显减少 ,与对照组比较 ,差异有极显著性意义 (均 P <0 .0 1) ,基质水肿减轻 ;而CD 19+阳性细胞浸润数与对照组比较 ,差异无显著性意义 (P >0 .0 5 )。结论 :口服萍芷片可影响慢性鼻窦炎鼻息肉组织中炎性细胞的浸润程度 ,有局部抗炎作用更多还原

【Abstract】 Objective:To assess the effects of taking the “Pingzhi Tablets” on infiltration of inflammatory in tissues of chronic sinusitis and nasal polyps.Method:Nasal polyps from taking the “Pingzhi Tablets” treated patients (40 cases) and untreated patients (40 cases) were investigated. The samples were stained by HE and SABC AP immunohistochemical methods.Result:Compared with untreated polyps, the polyps treated by taking the “Pingzhi Tablets” contained significantly lower tissue densities of CD 11b +, CD7+ positive cells. Although the densities of CD 19 + positive cells were lower in treated polyps, the differences were not statistically significant.Conclusion:The findings demonstrated tissue effects of treatment with taking “Pingzhi Tablets” and the treatment was effective in suppressing the inflammatory cell infiltration.更多还原