【摘要】 目的　为了寻求颅底斜坡区及其前方鼻咽部和蝶窦区肿瘤手术切除的最佳入路途径。方法　根据术前MRI所示肿瘤所在的部位和大小 ,采用LeFortⅠ型截骨进路对 1 6例该区域的肿瘤进行了手术切除 ,其中脊索瘤 8例 ,血管纤维瘤 2例 ,软骨瘤、骨髓瘤、垂体瘤、骨纤维结构不良、腺癌和粘液囊肿各 1例。结果　本组 1 6例颅底肿瘤 ,全切除 1 1例 ,次全切除 5例 ,随访 6～ 4 0个月。 4例局部复发 ,其余患者恢复良好。上颌骨复位后 ,咬合关系均恢复良好。结论　采用上颌截骨入路切除颅底肿瘤 ,较传统的前方或侧方入路对脑组织的损伤小 ,手术视野暴露清楚 ,无严重及长期的并发症发现更多还原

【Abstract】 Objective To explore an ideal approach for cranial base tumor excision. Methods The operation applied the approach of Le Fort I osteotomy in excising the tumors in the clival region of cranial base in 16 cases. Including chordoma 8 cases, angiofibroma 2 cases, chondroma, myeloma, pituitary adenoma, bone fibrous dysplasia, adenocarcinoma and mucid cyst each one case. Results The tumors of 11 cases were complete excisioned. The other 5 cases were subtotally excisioned. The syndrome disappeared or got better. Conclusion The approach of Le Fort I osteotomy is the best way for excising the tumor in the clival region of cranial base with little hurt to brain and minimal complications.更多还原