【摘要】 目的 :观察缬沙坦对老年原发性高血压 (EH)左室肥厚 (LVH)的逆转作用 .方法 :对 35例EH并LVH的患者口服缬沙坦 80～ 2 4 0mg ,每日 1次 ,疗程 1a .于治疗前、治疗 3个月、治疗 6个月和 1a后分别用彩色超声心动图测量有关参数 .结果 :缬沙坦不仅能有效降低老年高血压患者的收缩压和舒张压 ,而且能逐渐降低左室重量指数 (LVMI) ,P <0 0 0 1.结论 :长期使用缬沙坦治疗老年原发性高血压合并左室肥厚 ,能明显使左心室肥厚回缩 ,提高左心室收缩功能 ,进一步降低心脏危险因子 ,从而改善预后更多还原

【Abstract】 Objective: The effects of valsartan on the regression of left ventricular hypertrophy (LVH) in aged patients with essential hypertension (EH) were observed. Methods: 35 cases of hypertensive patients with LVH were given Valsartan 80～240?mg once daily for 12 months, LVH and cardiac function were assessed by echocardiography which were carried out before and after treatment. Results: The casual systolic and diastolic pressures in aged patients with EH decreased significantly after trearment and left ventricular mass (LVM) reduced (P<0 001) . Conclusions: (1) Hypertensive patients with SVH were given Valsantan for a long time. (2) The thinkness of left ventricular hypertrophy was decreased. The systolic function was improved, cardiac damage factors were decreased, and prognosis was improved.更多还原