【摘要】 目的　观察短程抗生素在预防外科手术区感染的效果。方法　 1 0 0例腹部外科手术患者被随机分为 2组 ,围手术期短程用药组 (术后用药 1d)及长程用药组 (术后用药 3d)预防手术感染。 2组患者在年龄性别及手术种类上均无差异。预防用抗生素为奈替米星合并使用甲硝唑。结果　短程用药组感染率为 2 % (1 5 0 )长程用药组感染率为 4 % (2 5 0 ) ,2组无明显差别。结论　围手术期短程应用抗生素即可有效预防术后手术区感染 ,从药物经济学和合理用药的角度来说也优于长期用药更多还原

【Abstract】 Objective To Observe the effect of antibiotics used for short term on preventing infection in surgery operational region Methods 100 abdominal operational patients were randomly assigned to 2 groups during perioperation:short-term group received antibiotics for 1 day and long-term group did for 3 days There were no difference in age,sex and operational variety between the two groups Preventive antibiotics were netilmicin and metronidazole administered together Results Infection rate of short-term group was 2%(1/50) and that of long-term group was 4%(2/50) There were no significantly different between the two groups Conclusions Antibiotics used in short term may effectively prevent post-operational infection in operational region during perioperation That was also better than long-term one on the part of drug economics and rational drug application更多还原