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环孢霉素A联合方案治疗骨髓增生异常综合征-难治性贫血45例报告

A regimen combined with cyclosporin A and androgen, all-trans retinoic acid in the treatment of myelodysplastic syndrome

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【作者】 方炳木裘红英李琳洁刘伟红金阳缙

【Author】 Fang Bingmu,Qiu Hongying,Li Lingjie,et al. (Department of Haematology, Fifth Affiliated Hospital of Wenzhou Medical college,Zhejiang Lishui City Central Hospital,323000)

【机构】 浙江省丽水市中心医院浙江省丽水市中心医院 丽水323000丽水323000

【摘要】 目的 探讨环孢霉素A联合方案治疗骨髓增生异常综合征-难治性贫血(MDS—RA)疗效。方法 对45例MDS—RA应用环抱霉素A、康力龙、维甲酸治疗观察3~6月以上。结果 总有效率73.33%(33/45),基本缓解37.78%(17/45),明显进步22.22%(10/45),进步13.33%(6/45),无效26.67%(13/45)。结论 环孢霉素A联合方案, 对MDS—RA有一定疗效。

【Abstract】 Objective To explore the therapeutic effectiveness of combination with cyclosporin A (CsA) and androgen,all-trans retionic acid (ATRA) in the treatment of myelodysplastic syndrome refractory anemia (MDS-RA). Methods Forty-five patients with MDS-RA were treated with CsA and androgen, ATRA. Results The overall efficacy and basic remission rate were73.33% and 37.78% , respectively. Conclusion The CsA combining reg- imen is efficacious for treating patients with MDS-RA.

  • 【文献出处】 江西医药 ,Jiangxi Medical Journal , 编辑部邮箱 ,2003年03期
  • 【分类号】R551.3
  • 【被引频次】2
  • 【下载频次】28
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