【摘要】 目的　探讨睾丸原发性恶性淋巴瘤 (primarytesticularlymphoma ,PTL)的临床病理、免疫组化特点、鉴别诊断。方法　分析 6例PTL的临床特点 ,观察组织病理切片和免疫组化标记并随访。结果　PTL多发生于中年以上成人 ,小儿亦可发生 ,1/ 3双侧罹患。免疫组化显示肿瘤细胞表达LCA、CD2 0、CD79α,不表达CK、PLAP、CD3、CD45RO。随访 2～ 2 0月 ,2例存活。结论　PTL为一种罕见的睾丸恶性肿瘤 ,多为弥漫性大B细胞型淋巴瘤 ,需与间变性精原细胞瘤或精母细胞瘤及胚胎性横纹肌肉瘤等鉴别。更多还原

【Abstract】 Objective To study the clinicopathology, immunohistochemical characteristic and differential diagnosis of primary testicular lymphoma(PTL).Methods Six cases of PTL were studied by clincopathology and imunohistochemistry,all cases were followed up.Restults PTL typically occurred during the adult but also did during the children.One third of cases showed damage of both testis.Immunohistochemistry showed the positive of LCA、CD20、CD79α and negative of CK、PLAP、CD3.Three cases were lived during 2～20 months.Conclusion PTL is a rare testicular neoplasms,most of which are diffuse large B cell lymphoma.It should be differentiated from anaplastic seminoma,spermatocytic seminoma and embryonal rhabdomyosarcoma etc.更多还原