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10例肠道恶性间质瘤的临床病理学及免疫组化特征

The Clinicapathological and Immunohistochemistry Features of 10 Cases of Intestinal Stromal Tumor

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【作者】 俞薇薇刘繁荣熊小亮肖雯

【Author】 YU Wei wei, LIU Fan rong, XIONG Xiao liang, XIAO Wen (Department of Pathology,Jiangxi Medical College,Nanchang 330006,China)

【机构】 江西医学院病理教研室江西医学院病理教研室 江西南昌330006江西南昌330006江西南昌330006

【摘要】 目的 :阐明肠道恶性间质瘤的临床病理学与免疫表型特征。方法 :收集 10例肠道间质瘤的临床病理资料 ,并进行免疫组化染色 ,标记抗体为CD34、CD117、VIM、S10 0、NSE。结果 :间质瘤的瘤细胞为梭形或上皮样、或二者混合存在 ,常排成束状、车辐状或栅栏状 ,CD34和CD117的阳性率分别为 80 %和 6 0 %。结论 :肠道间质瘤有较为独特的组织学形态 ,CD34和CD117联合使用有利鉴别诊断

【Abstract】 Purpose:To demonstrate the clinicopathological and immunophenotypical features of intestinal stromal tumor(IST).Methods:10 cases of intestinal stromal tumor were retrospectivel studied.All cases were immunostained using antibodies against CD34,CD117,Vimentin,S100 Protein,NSE.Results:The neoplastic cells of IST were spindle,epithelioid or both in different proportin.The histological spectrum included interlacing fascicles,storiform and palisading pattern.The positivity of CD34 and CD117 were 80%,60%,respectively.Conclusion:The characteristic histological features exist in IST.The detection of CD34 and CD117 is helpful to differential diagnosis.

  • 【文献出处】 江西医学院学报 ,Acta Academiae Medicinae Jiangxi , 编辑部邮箱 ,2003年02期
  • 【分类号】R735.3
  • 【被引频次】4
  • 【下载频次】51
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