【摘要】 目的　观察盐酸氟西汀治疗强迫症的临床疗效及不良反应。方法　对 6 3例强迫症患者予盐酸氟西汀治疗 ,以Y BOCS减分率作为疗效评定 ,以TESS量表评定不良反应。结果　 6 3例患者经 8周治疗后Y BOCS、HAMD、HAMA、NIMH总分均较治疗前有显著性差异。痊愈 (12 % )、显进(2 7% )、有效 (4 3% )、无效 (18% ) ;显效率 (4 0 % ) ,有效率 (82 % )。结论　盐酸氟西汀对强迫症治疗有效 ,不良反应轻微 ,耐受性好 ,有利于维持治疗更多还原

【Abstract】 Objective: To observe the clinical effectiveness and adverse effects of fluoxetine hydrochloride in treating patients with obsessive compulsive disorder (OCD). Methods: Fluoxetine Hydrochloride were administered to 63 patients with OCD. The reduction of Y BOCS was used for therapeutic effect evaluation and TESS for adverse effect assessment. Results: After 8 weeks treatment, total scores of Y BOCS, HAMD, HAMA and NIMH of 63 patients showed significant change compared with scores of pre treatment. The percentage of recovery, significant improvement, effectiveness, and no response was 12%, 27%, 43%, 18%, respectively, with 82% responsiveness rate. Conclusion: Fluoxetine hydrochloride shows therapeutic effect in OCD treatment with mild adverse effect and satisfactory tolerance, so may be beneficial for maintenance treatment.更多还原