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鼻病毒感染与儿童哮喘发作关系探讨

A study on the correlation of rhinovirus virus infections with asthma exacerbation in infants

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【作者】 邹映雪鲁继荣刘丽成换吉刘文东周亮康淑英

【Author】 ZOU Ying-xue,LU Ji-rong,LIU Li ,et al(The First Hospital of Jilin University,Changchun,130021,China)

【机构】 吉林大学第一医院儿科吉林大学第一医院儿科 吉林长春130021吉林长春130021吉林长春130021

【摘要】 目的:探讨儿童哮喘发作与鼻病毒感染的关系。方法:采用逆转录聚合酶链反应(RT-PCR)方法对72例哮喘发作期患儿进行鼻病毒(RV)检测,并进行不同年龄组病原分布情况比较,同时设立健康对照组。结果:72例哮喘发作期患儿中检出RV阳性病例29例(27.8%),与健康对照组相比差异有显著性;3岁以上年龄组RV感染率为51.9%(27/52),明显高于3岁以下组,两者差异有显著性。结论:小儿哮喘发作与RV感染密切相关,RSV是诱发3岁以上哮喘发作的主要因素。

【Abstract】 Objective To explore the relationship of rhinovirus(RV)with asthma exacerbation in children.Method To detect the RV frequently irritate acute respiratory tract infection in children in72cases with asthma exacerbation by reverse tran-scription-PCR(RT-PCR).Results Evidence of RV were obtained in29cases(27.8%)of the group of asthma exacerbation,in the group of >3years,27cases were found positive(51.9%),a significant difference was found in the two groups of different ages.Conclusion27.8%of the asthma attacks in children were precipitated by acute RV infections,the ratio in>3years was51.9%,RV was the most common agent in asthma exacerbation of >3years.

【关键词】 儿童鼻病毒哮喘
【Key words】 ChildrenRhinovirusAsthma
  • 【文献出处】 吉林医学 ,Jilin Medical Journal , 编辑部邮箱 ,2003年02期
  • 【分类号】R725.6
  • 【被引频次】5
  • 【下载频次】77
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