【摘要】 目的 :研究脐血瘦素水平与新生儿性别、孕周、出生体重、身高、体重指数及胎盘重量的关系。方法 :应用酶联免疫法 (ELISA)测定脐血瘦素水平 ,共测定了 4 6份样本 ,运用统计学方法分析其与新生儿性别、孕周、出生体重、身高、体重指数BMI(即体重除以身高的平方 ,单位为kg·m-2 )及与胎盘重量等的关系。结果 :脐血瘦素水平与出生体重、身高、体重指数及胎盘的重量有着显著性相关 ,而男女性别间脐血瘦素水平无显著性差异。结论 :脐血瘦素水平与新生儿孕周、出生体重、身高、体重指数及胎盘重量有密切关系 ,临床测定脐血瘦素水平对预测胎儿出生体重和生长发育有重要意义。更多还原

【Abstract】 Objective: To investigate the reletionship between the concentration of leptin with the sex, fetal weight, fetal height, fetal body mass index, gestational age and placental weight. Methods: Leptin concentrations in the serums of cord blood in 46 newborns(male=29,femal=17, gestational age 31～41 weeks, birth weigh 1.6～ 3.8 kg, birth height 35～52 cm) were measured by ELISA. The results were analyzed using SAS statistic software. Results: Leptin concentrations in the serums of cord blood were positively correlated with birth weight (r= 0.463, P< 0.01), birth height (r= 0.358, P< 0.05),body mass index (r= 0.328, P< 0.05) ,gestational weeks(r= 0.49, P< 0.01) and placental weight(r= 0.363, P< 0.05). Serum leptin levels of male neonates( 7.43± 10.03ng/mL) were not significantly different from those of female neonate( 8.87± 13.15 ng/mL) . Conclusion: There is significant relationship between the cord serum leptin and the fetal growth. They will be used as a meaningful parameter in evaluating fetal growth practically.更多还原