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抑郁症睡眠障碍与血清IL—2及sIL—2R水平的关系

Relationships between Serum Levels of IL-2 and sIL - 2R with Sleep Disorder in Depressive

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【作者】 祁富生贾福军郭新胜

【Author】 Qi Fusheng, Jia Fujun, Guo Xinsheng. (The Second Affiliated Hospital of Xinxiang Medical College, Xinxiang 453002)

【机构】 新乡医学院第二附属医院新乡医学院第二附属医院 453002453002453002

【摘要】 目的 探讨IL-2、sIL-2R与抑郁症睡眠障碍的关系。方法 采用酶联免疫吸附法(ELSIA)检测35例抑郁症和30名健康对照的血浆IL-2、sIL-2R水平。结果 抑郁症组IL-2水平低于对照组(P<0.05),且IL-2水平与睡眠表浅呈正相关关系(P<0.05);sIL-2R水平与对照组相比,无明显差异(P>0.05)。结论 抑郁症患者的睡眠表浅可能与血浆IL-2水平降低有关。

【Abstract】 Objective To explore the relationships between interleukin -2 (IL -2) and sIL -2R with sleep disorder in depressive. Methods Plasma levels of IL - 2 and sIL-2R in 35 cases of depressive and 30 controls were measured by enzyme linked immunosorbent assay (ELISA). Results IL - 2 levels in depressive group were lower then those in control group (P < 0. 05) , and their IL- 2 levels have positive relations with sleep situation (P < 0. 05) , There was no difference between the two groups (P > 0. 05) in sIL-2R level. Conclusions The sleep situation in depression was related with the plasma level of IL-2.

【基金】 河南省教育厅立项课题(20013200021)
  • 【文献出处】 神经疾病与精神卫生 ,Nervous Diseases and Mental Hygjene , 编辑部邮箱 ,2003年05期
  • 【分类号】R749
  • 【被引频次】3
  • 【下载频次】138
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