【摘要】 目的　比较丙泊酚及依托咪酯静脉诱导对罗库溴铵肌松效应的影响。方法　 30例ASAⅠ～Ⅱ级、择期胸部、腹部外科手术患者 ,随机分为丙泊酚诱导组 (1 5例 )、依托咪酯诱导组 (1 5例 )。两组术前和术中用药相同 ,用TOF GUARD加速度仪监测神经肌肉功能。结果　两种药物对罗库溴铵肌松效果的影响无显著性差异 (P >0 .0 5 )。结论　丙泊酚和依托咪酯静脉诱导对罗库溴铵肌松效应无明显影响更多还原

【Abstract】 Objective To compare the effect of propofol and etomidate on muscle relaxation of rocuronium.Methods Thirty ASA Ⅰ～Ⅱ patients aged 19～76 years undergoing selective thoracic and abdominal opertation were randomly divided into two groups: propofol group ( n =15) and etomidate group ( n =15). Anesthesia in propofol group was induced with propofol 1.5 ～ 2.0 mg/kg and rocuronium 0.6 mg/kg. Anesthesia in etomidate group was induced with etomidate 0.25 ～ 0.3 mg/kg and rocuronium 0.6 mg/kg. Dosage of preoperative medicine and anesthesia maintenance were not different in the two groups. Nerve muscle function was detected by TOF GUARD.Results There was no significant difference in the effects of propofol and etomidate on muscle relaxation of rocuronium ( P > 0.05 ).Conclusion Both propofol and etomidate had no obvious effect on muscle relaxation of rocuronium.更多还原