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围生期缺铁性贫血妇女血清转铁蛋白受体和铁蛋白的测定

Measurement of serum transferring receptor and serum ferritin in perinatal women with iron-deficiency anemia.

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【作者】 夏虹李栋邵华陈进苏汉桥

【Author】 Xia Hong, Li Dong, Shao Hua et al. Department of Laboratory, Renmin Hospital, Wuhan University, Wuhan 430060

【机构】 武汉大学人民医院检验科武汉大学人民医院检验科 430060 武汉430060 武汉

【摘要】 目的 探讨血清转铁蛋白受体(STfR)和血清铁蛋白(SF)测定对围生期妇女缺铁性贫血的诊断价值。方法 采用免疫透射比浊法测定STfR,免疫化学发光法测定SF,分别检测24例围生期贫血妇女(Ⅰ组),19例围生期未贫血妇女(Ⅱ组),20例感染或手术治疗育龄期妇女(Ⅲ组)和24例健康育龄期妇女(Ⅳ组),同时作血液常规分析。结果 STfR在Ⅰ组与Ⅱ组之间比较无显著性差异,但Ⅰ组与Ⅲ组、Ⅳ组比较有显著性差异,而STfR/lgSF在Ⅰ组和其它3组之间均有显著性差异。结论 STfR、STfR/lgSF是诊断围生期妇女缺铁性贫血,特别是轻度贫血的敏感指标。

【Abstract】 Objective To explore the diagnostic role of serum transferrin receptor (STfR) and serum ferritin (SF) in iron-deficiency anemia (IDA) of perinatal women. Methods Immunoturbidimetry was used to determine the concentration of STfR and chemoluminedcence assay to measure SF in 24 perinatal women with IDA (group I ), 19 perinatal women without IDA (group Ⅰ), 20 childbearing women subject to operation or infection (group Ⅲ) and 24 healthy childbearing women (group Ⅳ), respectively. Blood analysis was examined simultaneously. Results There was no significant difference in mean STfR between group Ⅰ and group Ⅱ (P>0.05), but there was significant difference between group Ⅰ and group Ⅲ or group Ⅵ (P<0.05), respectively. There was signficant difference in mean STfR/lgSF between group Ⅰ and other groups (P<0.05). Conclusion STfR and STfR/lgSF might be sensitive markers to diagnose IDA in perinatal women, especial mild IDA.

  • 【文献出处】 华中医学杂志 ,Central China Medical Journal , 编辑部邮箱 ,2003年01期
  • 【分类号】R446.6
  • 【被引频次】1
  • 【下载频次】43
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