【摘要】 目的 :为了掌握眼科杂志中随机或半随机及前瞻性的临床试验研究的情况 ,我们手检了眼科 7种主要杂志从创刊以来到 1999年止的随机 /半随机的临床前瞻性对照试验文献。方法 :据循证医学中心的手检纳入标准 ,严格按其要求将随机或半随机分组的前瞻性同期临床对照试验纳入 ,并分为随机临床对照试验 (RCT) ,和半随机临床对照试验 (CCT)。结果 :7种杂志中中华眼科是 5 0年创刊 ,其它 6种杂志多是 80年以后创刊 ,共发表文献 2 1317篇 ,RCT和CCT共检出 2 80篇 ,检出率 1 31% ,中华眼科杂志发表 179期 ,文献 74 2 8篇 ,RCT和CCT共 6 2篇 ,检出率 0 84 %。结论 :眼科杂志中 ,5 0、 6 0年代临床同期前瞻性的随机 /半随机对照试验少 ,70～80年代逐年增多 ,90年以后更多。其它 6种杂志也是RCT、CCT逐年增多更多还原

【Abstract】 Objective:In order to clarify the actual situations of the randomized control trial(RCT)or quasi-randomized trial(QRT)and prospective clinical experimental researches in the journals of opthalmology,the related materials from 7 major journals of opthalmology from the start publication up to the year of 1999 were hand searched.Method:We handsearching These journals hand searched. and according to the criteria of RCT and QCT were included according to Cochrane Center handsearch standards.Results:Seven Ophthalmologic Journals had 21317 papers,the RCT and QCT 280 papers were included,about 1.31%,A tolal of 7428 papers were in 179 issues of China Ophthalmologic Journal,62 papers could be included,about 0.84%.The RCT and QCT in the year of 60s are rare,after 1970,RCT and CCT increased year by year.Conclusion:As the Evidence-Based Medicine becoming gradually accepted of in clinical ophthalmology,the RCT and CCT would likely to be increased year by year in ophthalmologic journals.更多还原