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胶原蛋白-葡甘聚糖-软骨素共混膜的结构表征和物理性能研究

Structural characterization and physical properties of collagen-Konjac glucomannan-chondritin sulfate blend films

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【作者】 王碧张廷有王坤余但卫华叶勇

【Author】 WANG Bi~1,ZHANG Ting-you~1,WANG Kun-yu~(1,2),YE Yong~1,DAN Wei-hua~1Ministry of Education,Chengdu 610065,China);(Boimass Engineering Institute, Sichuan University, Chengdu 610065,China)

【机构】 四川大学皮革化学与工程教育部重点实验室四川大学皮革化学与工程教育部重点实验室 四川成都 610065四川成都 610065四川成都 610065 四川大学生物质工程研究所四川成都 610065四川成都 610065

【摘要】 用溶液共混法制备了胶原蛋白 葡甘聚糖 软骨素共混膜。并进行了FTIR,XRD,SEM分析及透光率抗张强度、断裂伸长率、吸水率、透汽性、吸附性和渗透性测试。结果表明:共混膜中胶原蛋白、葡甘聚糖及软骨素之间存在着强烈的相互作用和良好的相容性,三者共混明显改善了几种材料及二元共混膜的性能。该共混膜可望用作生物医用材料。

【Abstract】 Collagen-Konjac glucomannan-chondritin sulfate blend films was prepared successfully by the solvent-casting method. Their structure and properties were characterized by FT-IR, X-ray diffraction, SEM, optical transmittance, at the same time percent water absorption, tensile strength,elongation at break, water vapor permeability, adsorbability and penetrability were measured too. The results indicated that some strong interaction, and good compatibility existed among collagen/Konjac glucomannan and chondritin sulfate in the blend films.The water absorption and mechanical properties of it were improved markedly in comparation with binary duality blend films or each component. As a poetential biomaterial, the films will have a wide application in biomedical field.

【基金】 国家高技术发展计划(863计划)2001AA320609。
  • 【文献出处】 化学研究与应用 ,Chemical Research and Application , 编辑部邮箱 ,2003年06期
  • 【分类号】O484.4
  • 【被引频次】23
  • 【下载频次】279
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