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双功能化合物—二氯荧光素二丙烯酸酯的合成与生物活性

Studies on preparation,biological activity of 2,7-dichloro -3,6-acrylate fluorescin ester with di-function

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【Author】 TangHUI AnTang1,2,ZHI HuiWang3,KAI YinZhao1*,LIU FanWang2,PEI YanZhang3,RU DongYang2 (1.Department of Chemistry of Tianshui Normal University 741018 2.College of Chemistry and Chemical Engineering of LanZhou University 730000 3.Nice Chemical Engineering Coorporation of Zhejiang)

【机构】天水师院化学系；浙江纳爱斯化工股份有限公司；兰州大学化学化工学院；浙江纳爱斯化工股份有限公司；兰州大学化学化工学院甘肃天水　741001；甘肃兰州　730000；甘肃天水　741001；甘肃兰州　730000；

【Abstract】 In this paper 2,7Dichloro3,6Acrylate Fluorescin Ester has been prepared and characterized by elementary analysis,IR,UV,1HNMR,Flourensence spectra.Afterwards,its antitumor activity was tested.The results showed that it has good flourensence and antitumor activity and it is a prospective antitumor agent.Then,use it to pigmentate broad bean farian.The results show that it has good determination function for broad bean cells vitality.So it is a selective determination agent for broad bean cell vitality更多还原

【关键词】二氯荧光素二丙烯酸酯；抗肿瘤活性；蚕豆细胞生活力检测；
【Key words】 Preparation 2； 7-dichloro-3； 6-Diacrylate fluorescin ester antitumor agent selective determination agent for broad bean cell vitality；

【文献出处】化学研究与应用 ,Chemical Research and Application , 编辑部邮箱 ,2003年03期

【分类号】O623.624
【下载频次】97

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