节点文献
4-羟基-3-碘-5-硝基苯甲腈的新合成方法
A new method for the synthesis of 4-hydroxy-3- iodo-5-ni-trobenzonitrile
【摘要】 报道了以对羟基苯甲醛为原料,经过硝化、腈化和碘化反应合成牛羊抗肝片吸虫药4-羟基-3-碘-5-硝基苯甲腈的 新方法,总收率为76.9%,纯度达96.8%。
【Abstract】 A new method for preparation of 4-hydroxy-3~ iodo-5-nitrobenzonitrile used as a fasciolicide is reported. The title compound was synthesized from p-hydroxyben-zaldehyde by nitration, cyanation and iodination of the product. The total yield reaches 76. 9% and the purity is 96. 8%. The method has a feature of high yield and low cost.
【关键词】 4-羟基-3-碘-5-硝基苯甲腈;
对羟基苯甲醛;
抗肝片吸虫药;
合成;
【Key words】 4-hydroxy-3-iodo-5-nitrobenzonitrile; p-hydro-xy benzaldehyde) fasciolicide; synthesis;
【Key words】 4-hydroxy-3-iodo-5-nitrobenzonitrile; p-hydro-xy benzaldehyde) fasciolicide; synthesis;
- 【文献出处】 化学试剂 ,Chemical Reagents , 编辑部邮箱 ,2003年04期
- 【分类号】O625.67
- 【下载频次】205