【摘要】 目的 :探索羊水细胞染色体核型分析的方法 ,减少染色体病患儿出生。方法 :对 3 42例具有产前诊断指征高风险孕妇抽取孕中期羊水细胞培养 ,制备中期细胞染色体 ,G显带分析。结果 :发现 2 3例染色体异常 ,占 6 7%,其中数目异常 4例 ( 17 3 9%) ,结构异常 16例 ( 69 5 7%) ,嵌合体 3例 ( 13 0 4%)。结论 :羊水细胞的染色体核型分析是染色体病产前诊断的确诊方法之一。更多还原

【Abstract】 Objective To explore the use of amniocentesis in prenatal analysis,and reduce the newborn with abnormal chromosome.Methods Amniocentesis was employed to detect amniotic cells collected from 342 pregnant women with high-risk prenatal diagnosis indications.Results It was shown by karyotype analysis that 23 cases(6.7%) were found with abnormal karyotype,in which 4 cases(17.89%) were found with abnormal numbers,16 cases(69.57%) were found with abnormal construction,and 3 case(3.04%) were somatic mosaicism.Conclusions It is indicated that amniocentesis and karyotyping is one of the most important methods for prenatal diagnosis. [更多还原