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抗环瓜氨酸多肽抗体对类风湿关节炎的诊断价值

THE DIAGNOSTIC VALUE OF ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY FOR THE PATIENTS WITHRHEUMATOID ARTHRITIS

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【作者】 夏乾峰覃西钱士匀巫翠萍

【Author】 XIA Qian-feng,QIN xi,QIAN Shi-yun,et al. (Department of Medical Laboratory The Affiliated Hospital of Hainan Medical College,Haikuo 571101,China)

【机构】 海南医学院检验系海南医学院检验系 海口571101海口571101海口571101

【摘要】 目的:探讨抗环瓜氨酸多肽(CCP)抗体作为类风湿关节炎(RA)实验室诊断的一个新指标的临床价值。方法:采用测抗CCP抗体的ELISA试剂盒对确诊46例RA病人和40例健康对照者以及30例非RA弥漫性结缔组织病患者血清进行检测。结果:抗CCP抗体对RA诊断的敏感性、特异性为61%和96%。结论:在临床应用中,抗CCP抗体是诊断RA的一个特异指标。

【Abstract】 Objective To explore the diagnostic value of anti-cyclic citrullinated peptide anti-CCP antibody as a new laboratory mark for the patients with rheumatoid arthritis(RA. Methods Three groups were recruited in this study:RA patients group(n=46),control group(n=40), diffuse connective tissue diseases patients(n=30). Anti-CCP antibody was detected by ELISA kit. Results The sensitivity and specificity of anti-CCP antibody in the diagnosis of RA were 61% and 96 % respectively. Conclusion Anti-CCP antibody is a specific mark for the RA diagnosis in clinicaapplication.

  • 【文献出处】 海南医学院学报 ,Journal of Hainan Medical College , 编辑部邮箱 ,2003年06期
  • 【分类号】R593.22
  • 【被引频次】1
  • 【下载频次】48
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