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抗环瓜氨酸多肽抗体对类风湿关节炎的诊断价值
THE DIAGNOSTIC VALUE OF ANTI-CYCLIC CITRULLINATED PEPTIDE ANTIBODY FOR THE PATIENTS WITHRHEUMATOID ARTHRITIS
【摘要】 目的:探讨抗环瓜氨酸多肽(CCP)抗体作为类风湿关节炎(RA)实验室诊断的一个新指标的临床价值。方法:采用测抗CCP抗体的ELISA试剂盒对确诊46例RA病人和40例健康对照者以及30例非RA弥漫性结缔组织病患者血清进行检测。结果:抗CCP抗体对RA诊断的敏感性、特异性为61%和96%。结论:在临床应用中,抗CCP抗体是诊断RA的一个特异指标。
【Abstract】 Objective To explore the diagnostic value of anti-cyclic citrullinated peptide anti-CCP antibody as a new laboratory mark for the patients with rheumatoid arthritis(RA. Methods Three groups were recruited in this study:RA patients group(n=46),control group(n=40), diffuse connective tissue diseases patients(n=30). Anti-CCP antibody was detected by ELISA kit. Results The sensitivity and specificity of anti-CCP antibody in the diagnosis of RA were 61% and 96 % respectively. Conclusion Anti-CCP antibody is a specific mark for the RA diagnosis in clinicaapplication.
【Key words】 Anti-CCP antibody; arthritis rheumatic; clinical test; serodiagnosis;
- 【文献出处】 海南医学院学报 ,Journal of Hainan Medical College , 编辑部邮箱 ,2003年06期
- 【分类号】R593.22
- 【被引频次】1
- 【下载频次】48