【摘要】 以苯胺为原料,经双乙烯酮在甲苯中酰化得乙酰乙酰苯胺;在氯仿中溴化得溴乙酰乙酰苯胺;然后在浓硫酸中环合制得4 溴甲基 2(H) 喹啉酮。结果表明:合成总收率为62 5%,含量达98 6%。该法原料易得,操作简便,总收率高。更多还原

【Abstract】 4-Bromoethyl 2(H) quinolinone was synthesized by the acylation of aniline with biketene in toluene, the bromination in chloroform, and the cyclization in sulfuric acid. The result shows that the overall yield is 60.36% and content up to 98.6%. The raw material can be gotten easily using the method. The operating process is simple, and the yield is high.更多还原