【摘要】 目的　对使用长春碱类药物或化疗后产生粒缺并发肠道感染而导致中毒性肠麻痹的治疗进行探讨。方法　对 10例中毒性肠麻痹在禁食、胃肠减压、补充电解质、纠正酸碱失衡、肛管排气、抗生素等使用的基础上 ,加用NS 15 0ml+阿拉明 10mg +酚妥拉明10～ 2 0mg快速静滴 ,每日 1～ 2次 ,连用数天。为加强疗效 ,在静滴完上述溶液后半小时 ,可加肌注新斯的明 0 5～ 1mg。结果　本组中 ,使用该方法治疗 9例 ,其中 7例有效。结论　应用阿拉明 +酚妥拉明配合新斯的明对使用长春碱类药物或化疗后产生粒缺并发肠道感染等导致中毒性肠麻痹疗效好 ,值得进一步研究。更多还原

【Abstract】 Objective To study the treatment for toxic enteroparalysis after using Vinblastinums or chemotherapy which leads to agranulocytosis combining with intestinal infection. Methods It was based on treatment such as food prohibiting, gastro-intestinal relieving ,9 cases of toxic enteroparalysis were quickly intravenous dropped with NS 150 ml, phentolamine 10～20 mg and Aramine 10 mg one or two times a day for several days. In order to improve the effect, after half an hour of the therapy , 0.5～1 mg neostigmine were intramuscularly injected. Result Among 10 patients, 9 cases received the treatment, the efficacy for 7 cases. Conclusions Using of Aramine ?Phentolamine combining with neostigmine is a effective treatment for toxic enteroparalysis , and worth future studying.更多还原