节点文献
TDI的急毒实验及其对骨髓微核率的影响
Acute toxicity experiment of TDI and influence of TDI on micronucleus of mice bone marrow
【摘要】 研究了2,4-甲苯二异氰酸酯对小鼠的急性经口的毒性以及其对小鼠骨髓嗜多染红细胞微核率的影响.2,4-甲苯二异氰酸酯小鼠经口的LD50为1995mg kg;在分别给予小鼠1 2LC50、1 4LC50剂量的2,4-甲苯二异氰酸酯的染毒组与阴性对照组比较,差异呈显著性.
【Abstract】 Studied the acute toxicity effect of 2,4tolylene diisocyanate on mice by mouth and the influence of micronucleus frequency of mice bone marrow. Results: The results showed that the LD50 of 2,4tolylene diisocyanate on mice by mouth was 1995mg/kg; at the dosage of 1/2 LC50 ?1/4 LC50 , the different between the group of TDI and the group of negative control was distinct.
【基金】 国家自然科学基金项目(30271108);黑龙江省重点实验室研究基金.
- 【文献出处】 哈尔滨商业大学学报(自然科学版) ,Journal of Harbin University of Commerce(Sciences Edition) , 编辑部邮箱 ,2003年05期
- 【分类号】R114
- 【被引频次】12
- 【下载频次】191