【摘要】 合成了七个稀土丙二酸类配合物(RE2(C3H2O4)3,RE=Sm,Eu,Gd,Dy,Nd)、1,1-环丁烷二羧酸铕(Eu2(C6H6O4)3)和1,1-环戊烷二羧酸铕(Eu2(C2H8O4)3),其中1,1-环丁烷二羧酸铕和1,1-环戊烷二羧酸铕稀土配合物为首次报导。经元素分析、红外光谱、热分析确证了它们的组成为RE2A3·nH2O(n=6,3,2)。体外抗肿瘤活性实验表明有一定的细胞毒活性。更多还原

【Abstract】 Seven complexes of rare earth and malonic [RE2 (C3H2O4) 3, RE = Sm, Eu, Gd, Dy, Nd], cyclobutane-1, 1 - dicarboxylic acid, cyclopentane- 1,1 - dicarboxylic acid are prepared, and it is first reported that complexes of Europium and cyclobutane - 1, 1 - dicarboxylic acid, cyclopentane-1, 1-dicarboxylic acid have been synthesized. The complexes are confirmed by element analysis and IR. The results show that the complexes have cytotoxicity on HeLa cells for 48 h in vitro.更多还原