【摘要】 目的 探讨塑料生产中职业接触内分泌干扰物对女工月经功能的影响。方法 应用整群抽样方法和女性生殖情况调查表,对塑料厂作业女工(观察组)及非塑料作业女工(对照组)共719人进行自评问卷调查。结果 (1)观察组女工月经异常发生率明显高于对照组,且经期、经量和周期异常的发生率均显著高于对照组(P<0.05)。(2)观察组女工经期和经量异常在不同工龄段间差异有显著性(P<0.05),但不存在线性关系。(3)将月经异常的影响因素进行Logistic回归分析,发现接触毒物与月经异常有显著意义(P<0.05)。结论 塑料作业中接触内分泌干扰物可对女工月经功能产生不良影响,提示有必要做进一步研究,以便采用措施,保护女工健康。更多还原

【Abstract】 Objective To study the effects of occupational exposure to endocrine disrupters (ECDs) in plastic plants. Methods 719 female workers including observation group exposed to plastic manufacture production environment and control group not exposed to plastic manufacture production environment were selected by the cluster sampling method and were investigated using the unified questionnaire on female reproductive function. Results The observation group showed significantly higher prevalence rates of abnormal menstruation, and irregular menstrual period, menstrual cycle and menstrual quantity compared with those of control group (P<0.05). There was a significaut difference, according to break of duration of employment in irregular menstrual period and irregular menstrual quantity in observation group (P<0.05), whereas there was no linear relationship between abnormal menstruation and duration of employment. The risk factors of abnormal menstruation were analyzed by Logistic regression, the results showed that only exposure to endocrine disrupters was significantly associated with abnormal menstruation (P<0.05). Conclusion It seemed to be harmful to the menstrual function for female workers exposed to endocrine disrupters in production process of plastic manufacture. Further study should be carried out to make countermeasure protecting health of female workers.更多还原