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乙型脑炎患儿脑脊液细胞因子含量检测的临床意义
Clinical significance of detection of cytokines in cerebrospinal fluid(CSF) in children with encephalitis B
【摘要】 目的 探讨乙型脑炎患儿脑脊液细胞因子含量的变化。方法 应用免疫化学法测定了 3 8例乙型脑炎患儿脑脊液中 IL - 6、IL - 8、TNF水平。结果 乙型脑炎患儿脑脊液中 IL - 6、IL - 8、TNF含量均高于正常儿 ( P<0 .0 0 1)。结论 细胞因子不仅具有抗病毒作用 ,而且也参与了小儿乙型脑炎的病理过程
【Abstract】 Objective To study the changes of cytokins in CSF in children with encephalitis B.Methods Thirty-eight patients with encephalitis B were tested with immunological chemistry methods for levels of CSF IL-6,IL-8?TNF.Results IL-6?IL-8?TNF levels in children with encephalitis B were higher than those in normal controls(P<0.001).Conclusion These cytokines not only have anti-viral effect,but also play a role in pathogenesis of encephalitis B in children.
【关键词】 脑炎,日本;
白细胞介素-6;
白细胞介素-8;
肿瘤坏死因子;
【Key words】 Encephalitis; Cytokine-6(IL-6); Cytokine-8(IL-8); Tumor necrosis factor(TNF);
【Key words】 Encephalitis; Cytokine-6(IL-6); Cytokine-8(IL-8); Tumor necrosis factor(TNF);
- 【文献出处】 淮海医药 ,Journal of Huaihai Medicine , 编辑部邮箱 ,2003年02期
- 【分类号】R725.1
- 【下载频次】28