【摘要】 目的 :了解过敏性紫癜 (HSP)患儿血D—二聚体的水平及其临床价值。方法 :用单克隆抗体乳胶凝集试验法测定 32例HSP患儿血D—二聚体水平 ,同时测凝血象。结果 :所有患儿凝血象正常 ,紫癜性肾炎组血浆D—二聚体阳性率显著高于无肾炎组 (P <0 .0 5 )。结论 :D—二聚体的测定能早期、快速、准确的判断HSP患儿体内的高凝状态程度 ,以便及时有效地使用抗凝药物阻止或延缓毛细血管血栓形成 ,对减轻并发症 ,缩短病程 ,防止复发十分重要。更多还原

【Abstract】 Objective: To evaluate the plasma level and clinical volume of D-dimers in children with Henoch-Schonlein purpura(HSP). Methods:The plasma levels of D-dimers in 32 HSP patients were measured by monoclonal antibody latex agglutination test, to detect hemocoagulation at the same time. Results: The hemocoagulation in all patients is normal, the positive rate of plasma D-dimer increased significantly in patients with Henoch-Schonlein Nephritis than those in patients without Henoch-Schonlein Nephritis(P<0.05). Conclusion: The detection of plasma D-dimers makes it early,fast and exact to judge the body’s hypercoaguliability degrees in the patients with HSP , so that anticoagulative drugs can be effectively used to hold back or delay the capillary vessel thrombosis in time. It is important for alleviating complications,shortening course of disease and preventing relapse.更多还原