【摘要】 目的　进一步探讨焦炉工人职业性肺癌的病因。方法　采用多种致癌因子诱发小鼠肺癌的实验。结果　二苯并 [a ,h]蒽的致癌作用强于苯并 [a]芘 ,五环烃同焦尘相复合后 ,致癌作用呈现相加效应。结论　五环烃 ,尤其是二苯并 [a,h]蒽 ,作为多环芳烃致癌原的代表 ,是焦炉工人职业性肺癌的主要病因。更多还原

【Abstract】 Objective To further explore the etiology of occupational lung cancer among coke oven workers. Methods Induce mice lung cancer by different kinds of carcinogens.Results DB[a,h]A is more carcinogenic than B[a]P . Carcinogenic effect might be increased by exposure to pentacyclic hydrocarbons and coke dust simultaneously.Conclusions The pentacyclic hydrocarbons,especially the DB[a,h]A, a representative carcinogen of this group,might be the main carcinogen for occupational lung cancer among coke oven workers.更多还原