【摘要】 目的 了解近10年烧伤病区感染病原菌的变迁和葡萄球菌的耐药性。方法 比较1992～1996年和1997～2001年两组烧伤病人的创面培养、血培养和静脉导管培养结果,对细菌检出及葡萄球菌的药敏进行综合分析。结果金黄色葡萄球菌的检出率占第一位,铜绿假单胞菌的检出率也在增加,尤其是血培养和静脉导管培养,两组比较,差异有显著性(P<0.05)。万古霉素对耐甲氧西林金黄色葡萄球菌(MRSA)有很高的抗菌活性,敏感性为100％,其次是复方新诺明,其余抗生素对MRSA的抗菌活性较差。结论 金黄色葡萄球菌和铜绿假单胞菌是烧伤病区的主要病原菌,万古霉素等糖肽类抗生素是治疗MRSA感染的可靠药物。更多还原

【Abstract】 Objective To study the changes of pathogens of bum infection and antimicrobial resistance of Staphylococci. Methods Bacterial culture results of wound, blood, venous catheter were compared between 1992-1996 and 1997-2001, and drug sensitivity of Staphylococci was analysed. Results The most common pathogens were S. aureus , P. aeruginosa was the next, vancomycin showed the excellent activity against methicillin - resistant S. aureus (MRSA), followed by SMZ, the other antimicrobial agents showed poor activity against MRSA. Conclusions S. aureus and P. aeruginosa were main pathogens in burn patients, vancomycin was effective antibiotics for the treatment of infections caused by MRSA.更多还原