节点文献
血管内皮生长因子缓释微粒的合成与制备
The Synthesis and Fabrication of Relasing Slowly PLAGA Micropaticles with VEGF
【摘要】 目的 探讨乳化-分散法合成与制备血管内皮生长因子缓释微粒的效果。方法 采用乳化-分散法,使用可生物降解高分子聚乳酸/乙醇酸共聚物(PLGA)对血管内皮生长因子(VEGF)进行包裹,制成可控制释放的微粒。结果 此方法制得了0.2～0.33μm的含VEGF的缓释微粒。结论 乳化-分散法是合成与制备血管内皮生长因子缓释微粒的较好方法之一。
【Abstract】 Objective To research the effect on synthesis and fabrication of releasing slowly PLGA microparticles with VEGF. Methods The method of emulsifi cation - diffusion was to incorporate VEGF into microparticles composed of biodegradable PLGA. The controlled release of microparticles were acquired. Results The size of releasing slowly PLGA microparticles with VEGF was 0.2 - 0.33 μm. Conclusion The method of emulsification - diffusion is a good way to synthesis and fabricate the releasing slowly PLGA microparticles with VEGF.
【基金】 深圳市科技计划基金(编号200204061)
- 【文献出处】 骨与关节损伤杂志 ,The Journal of Bone and Joint Injury , 编辑部邮箱 ,2003年11期
- 【分类号】TQ463
- 【被引频次】1
- 【下载频次】87