【摘要】 目的　探讨高流量吸氧 (高氧 )综合治疗 (HOCT)椎动脉型颈椎病的疗效及其诊断基础研究。方法　解剖观察了 6 0例成人脊柱颈段标本 ,发现 5例颈椎钩椎关节骨赘压迫椎动脉的情况与临床椎动脉磁共振血管成像 (MRA)作了诊断对比分析。回顾性分析了 182例HOCT临床资料。病人以高氧治疗为主 ,配合口服中西药物 ,神经阻滞、颈按摩复位、颈围领固定等措施同步综合治疗。应用椎动脉经颅多普勒超声血流显像 (TCD)治疗前后血管情况比较。高氧综合治疗组和非高氧综合治疗 (NHOCT)对照组的疗效进行比较。结果　椎动脉在病变标本上受压迫的表现与临床MRA改变基本一致。对双椎动脉(DVA)及基底动脉 (BA)平均血流速度 (Vm)与收缩期最高峰血流速度 (Vs)平均参数作治疗前后比较 ,差异显著 (P <0 0 5 )。HOCT组经 6个月～ 4年的随访 ,按分级标准分析 ,总有效率为 92 9% ,差及无效率为 7 1%。NHOCT组 (180例 )有效率为 35 4 % ,差及无效率为 6 4 6 %差异显著 (P <0 0 5 )。结论　TCD及MRA是椎动脉型颈椎病无创及可靠诊断方法。椎动脉痉挛、弯曲是HOCT的适应证 ,而椎动脉受压至管腔狭窄是手术的适应证。HOCT的作用在于增加血氧含量 ,降低血液粘稠度 ,减少血小板凝聚 ,改善微循环 ,扩张血管及解除骨赘因压迫椎动脉导致痉挛更多还原

【Abstract】 Objective To study the diagnostic and the efficacy of hyper oxygen in complex treatment (HOCT) of the vertebral artery type of cervical spondylosis (VACS).Methods Five cases of the Luschks joint osteophyet found at the spinal column specimens (60 cases) were dissected and compared with MRA images obtained from the clinic.The data of 182 cases of VACS were analyzed retrospectively.The patients mainly received HOCT combined with oral adminstration of traditional chinese and western medicine,nerve blocking,cervical sitting massage,the skill reduction of cervical vertebral,fixation with cervical collar etc.Using the transcranial doppler (TCD) imaging,the companion was performed between before and after treatment were compared.Therapeutic effective of HOCT group was compared with non hyper oxygen in complex treatment (NHOCT) control group.Results The features of vertebral arteries being pressed by the osteophytes at the specimens were sameness to that on the MRA.The TCD flow imaging between before and after treatment revealed that.The difference between before and after treatment was significant (P<0 05).HOCT group:With following up 6 months-4 years,182 cases were observed and analysed according to the grade standard.The excellent were 92 9%,no good were 7 1%.NHOCT control group:180 cases were observed,the excellent were 35 4%,no good were 64 6%.The difference between two groups was significant (P<0 05).Conclusion The TCD and MRA are dependable diagnostic method for the VACS.The curative effect of HOCT includes:increasing the blood oxygen,reducing the blood viscosity and platelet aggregation,improving the microcirculation;expanding the vessel diameter and relaxing the spasm of the vertebral artery etc.Following the blood flow turns to normal,the symptoms e g the postural dizziness would be cured.更多还原