【摘要】 目的 :观察肝硬化并自发性细菌性腹膜炎 (SBP)患者血清和腹水中一氧化氮 (NO)水平的变化及临床意义。方法 :肝硬化腹水 72例分为SBP组 (n =4 0例 )和漏出液组 (n =32例 ) ,采用Gress法测定两组患者血清和腹水的NO的变化。结果 :SBP组血清和腹水的NO水平明显高于漏出液组 (P <0 .0 1 ) ;SBP组腹水NO水平又明显高于血清中的NO水平 ,且随着感染的控制 ,腹水中NO水平明显下降 (P <0 .0 1 )。结论 :腹水NO的检测有助于SBP的诊断和疗效观察更多还原

【Abstract】 Objective:To study the clinical significance of serum and ascitic fluid nitric oxide (NO) levels in patients with cirrhosis and spontaneous bacterial peritonitis(SBP).Methods:NO contents were detected by Gress method in 40 cirrhotic patients with SBP and 32 cirrhotic patients without SBP.Results:Serum and ascitic fluid NO levels were high in patients with SBP as compared with those without SBP( P <0.01).In SBP patients,NO levels from ascitic fluid were superior to those from serum,and there was an obvious decrease of ascitic fluid NO levels with the control of infection ( P <0.01).Conclusion:Detection of NO levels from ascitic fluid is helpful to diagnosing SBP and evaluating the efficacy.更多还原