【摘要】 目的 :建立安钠咖注射液中苯甲酸钠与咖啡因的主成分回归测定法。方法 :采用主成分回归法同时测定安钠咖注射液中各组分含量 ,且与药典方法测定的结果进行了比较。结果 :主成分回归法测得苯甲酸钠与咖啡因的平均回收率和相对标准偏差分别为 99.7% ,1.0 6%与 99.2 % ,0 .94% ,与药典方法比较 ,两者所测结果差异无显著性 (t检验 )。结论 :主成分回归法快速、准确 ,可同时测定复方药物制剂中的多组分更多还原

【Abstract】 Objective:To establish a principal component regression(PCR) method for the determination of caffeine and sodium benzoate in annaka injection . Method: All compounds in annaka injection were determined simultaneously by principal component regression,the results obtained by PCR were compared with those obtained by the standard method. Results: The average recovery and the relative standard deviation of sodium benzoate and caffeine obtained by PCR were 99.7%,1.06% and 99.2%,0.94 % respectively . It was shown by t test that there was no significant difference between the results of PCR and standard method. Conclusion: The PCR is rapid and accurate . It can be applied to multicomponent analysis of compound pharmaceutical preparations.更多还原