节点文献

含对溴苯基的新型DNA切割剂的合成及活性研究

Synthesis and Cleaving Activity of DNA Photocleaver Containing Bromoacetophenone

推荐 CAJ下载
PDF下载
不支持迅雷等下载工具，请取消加速工具后下载。

【Author】 LI Li-Hua, LIU Dan, TANG Fei-Li, YUAN Gu * (Key Laboratory of Bioorganic and Molecular Engineering of Education Ministry, Department of Chemical Biology, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China)

【机构】北京大学化学与分子工程学院化学生物学系；生物有机与分子工程教育部重点实验室；生物有机与分子工程教育部重点实验室北京100871；北京100871；北京100871；

【Abstract】 A novel DNA photocleaver containing bromoacetophenone-polyamide was synthesized by DCC coupling reaction in the presence of DMAP, and its DNA cleaving activity was investigated by using pBluescript SK DNA by method of gel electrophoresis. The result shows that the photocleaver containing bromoacetophenone-polyamide has a remarkable cleaving activity for pBluescript SK DNA.更多还原

【关键词】寡聚酰胺； DNA识别分子； DNA切割剂；
【Key words】 Polyamide； DNA recognition molecules； DNA-photocleavage agents；

【基金】国家自然科学基金 (批准号 :39970 16 9,2 9872 0 0 1)资助

【文献出处】高等学校化学学报 ,Chemical Research In Chinese Universities , 编辑部邮箱 ,2003年08期

【分类号】O658.9
【被引频次】2
【下载频次】90

知网节下载

节点文献中：

本文链接的文献网络图示:

本文的引文网络

节点文献