Objective To study the level change of serum type - Ⅳ collagen (Ⅳ-C) and Hyaluranate (HA) in chronic hepatitis and h'ver cirrhosis patients and their value in diagnosis of liver cirrhosis. Method solid phase - sandwich - enzyme immunoassay was used to recorder the level of Ⅳ -C and HA in 96 chronic HBV hepatitis and liver cirrhosis patients and compared with 20 normal people. Result The serum level of HA and Ⅳ-C was correlated with the degree of hepatic fibrosis. Compared with normal people and mild chronic...