【摘要】 目的 :探讨多发性内分泌腺瘤Ⅱa型 (MENⅡa)的MRI表现 ,提高对该病的认识和诊断水平。方法 :回顾性分析经临床手术病理证实的 4例患者MRI资料 ,4例均行MRI平扫和增强扫描。结果 :MENⅡa的MRI表现 ,嗜铬细胞瘤均发生在肾上腺 ,平扫表现为有完整包膜的信号均匀或不均匀的肿块 ,增强后呈不均匀强化 ,MRI特异性表现为T2 WI呈明显高信号 ,出血、坏死、囊腔形成表现为信号不均匀。甲状腺髓样癌 (medullarythyroidcarcinoma ,MTC) :肿瘤在T1WI上可为略低、略高或等信号 ,在T2 WI上为不均匀高信号 ,转移淋巴结在STIR序列上呈明显高信号 ,增强后不均匀强化 ,淋巴结边缘明显强化 ,中央呈低信号。结论 :MRI对MEN Ⅱa的诊断及鉴别诊断具有重要价值 ,对评价肿瘤与周围结构的关系和制订手术方案十分重要更多还原

【Abstract】 Objective:To explore MRI features of multiple endocrine neoplasia Ⅱa (MENⅡa),and to improve the diagnostic ability and understanding of the disease.Methods:The MRI features of MENⅡa in 4 patients proved by surgery and pathology were reviewed retrospectively.All patients received plain and enhanced MR imaging.Results:All pheochromocytomas in this series located in adrenal gland with homogeneous or heterogeneous signal on plain MRI and heterogeneous on enhanced MRI.MR characteristic of the disease was prominently high signal on T 2WI.Heterogeneous signal was due to formation of cyst,necrosis and hemorrhage.Medullary thyroid carcinoma appeared as hypointensity,hyperintensity or iso signal on T 1 weighted and heterogeneous hyperintensity on T 2 weighted MR imaging.The metastatic lymph nodes were prominently hyperintense on STIR,and circular enhancement was often observed on postcontrast image.Conclusion:MRI is valuable for the diagnosis and differential diagnosis of MENⅡa,and is important in the delineation of tumor extent and surgical planning.更多还原