【摘要】 目的探讨影响甲状腺髓样癌预后的因素。方法采用统计学单因素及多因素分析方法,研究64例甲状腺髓样癌的预后因素。结果根据Kaplan-Meier累积生存率算法,64例病人5年、10年、15年生存率分别为90.47％、82.47％、74.89％。单因素分析显示:年龄、T分期、颈部淋巴结转移与否、颈部淋巴结清扫术式、是否伴有内分泌症状均明显影响预后。多因素分析中,只有年龄、T分期和是否伴有内分泌症状是影响患者预后的独立因素。结论早期诊断和早期治疗能明显改善甲状腺髓样癌患者的预后。更多还原

【Abstract】 Objective To investigate the prognostic factors in patients with medullary thyroid carcinoma. Methods Sixty four patients with medullar, thyroid carcinoma were treated from October 1963 to December 1990. The prognosis factors of those patients were studied by univariate analysis and multivariate analysis methods. Results The survival rate of 5 -year, 10 - year and 15 - year was 90.47 % (58 / 64), 82.47 % and 74.89 % respectively. The univariate analysis showed that the significant prognostic factors were age, T stage, lymph node metastasis and endocrine change. The multivariate analysis showed that age, T stage and endocrine change were prognostic factors respectively. Conclusion The significant prognostic factors could be age, T stage, lymph node metastasis and endocrine change in patients with medullary carcinoma.更多还原