【摘要】 采用扫描和透射电子显微镜研究大鼠侧脑室及其脉络丛室管膜上皮的超微结构特征 ,并探讨其功能。扫描电镜观察结果 :侧脑室壁室管膜上皮细胞游离端呈不规则多边形 ,可见纤毛及微绒毛 ,偶见分泌泡。脉络丛上皮细胞游离端微绒毛及分泌泡丰富 ,纤毛少见 ,可见“丛上细胞”。透射电镜观察发现 :侧脑室壁及脉络丛上皮均由单层立方上皮组成 ,但二类上皮细胞的超微结构明显有别。室管膜上皮表面可见纤毛及微绒毛 ,分泌泡少见 ;脉络丛上皮游离端微绒毛丰富 ,常吻合成迷路样网 ,微绒毛的顶端膨大 ,形成微顶浆分泌小泡 ,胞浆内细胞器丰富。大鼠侧脑室壁及脉络丛上皮超微结构的差异反映二者功能的不同。本研究认为侧脑室脑脊液分泌的主要部位是脉络丛 ,其分泌的方式除脉络丛上皮细胞的主动运输功能外 ,可能微顶浆分泌法是侧脑室脑脊液形成的主要方式更多还原

【Abstract】 The ultrastructural features and functions of ependymal epithelium of lateral ventricle and its choroid plexus in rats were studied by scanning and transmission electron microscopy. Results of the scanning electron microscopy study: The ependymal cells of lateral ventricle observed from the free surface were unregular polygon with many cilia, microvilli and occasionally secretory vesicles. There were many microvilli, secretory vesicles and few cilia on the surface of choroid plexus epithelium. Epiplexus cells aslo could be found. Observation of transmission electron microscopy: The epithelium of lateral ventricle and its choroid plexus were both simple cuboidal epithelium, but with two kinds of obviously different ultrastructure. Cilia, microvilli and few secretory vesicles could be found on the free surface of ependymal cells in lateral ventricle, while microvilli on choroid plexus epithelium were abundant and formed labyrinthic web, with its terminal swelling into microapocrinic vesicles. The ultrastructural difference between the epithelium of floor and choroid plexus of lateral ventricle in rats inflected their functional difference. The study suggested that the lateral ventricle choroid plexus was the mian part of cerebrospinal fluid(CSF) secretion. At the same time, microapocrine may be the main mode of CSF formation in lateral ventricle, besides the active transportation of the epithelium of choroid plexus.更多还原