【摘要】 目的探讨辐照氟银猪皮覆盖自体微粒皮移植治疗深度烧伤的可行性及实用性。方法将所取的自体刃厚皮剪碎至小于1 mm3,取大张辐照氟银猪皮平铺,在真皮面涂一层厚约2 mm欣纳星软膏,用绸布转移法将自体微粒皮转移至猪皮上,再将猪皮移植至已切(削)痂的烧伤创面上,缝合固定好,在低位剪孔引流,厚敷料加压包扎固定,避免长时间受压。观察术后微粒皮生长愈合情况,制定疗效判断标准。结果猪皮涂一层欣纳星软膏后,对微粒皮的粘附力提高。临床应用15例,移植覆盖面积为(12.3±3.5)%,供/受皮区面积比为1∶(11.0±2.7),愈合时间为(27.5±5.5)d,其中一类愈合9例、二类愈合6例,临床效果接近用异体皮覆盖的效果。结论辐照氟银猪皮覆盖自体微粒皮移植治疗深度烧伤,操作简便,节省皮源,价格低廉,临床效果较好。更多还原

【Abstract】 Objective To study the feasibility of using irradiated porcine skin impregnated with fluorine and silver covered by autogenous skin granule graft in the treatment of severe burn injury. Methods Autogenous split-thick skin grafts were cut into small pieces (<1 mm 3 ), which were transferred onto the sheet of porcine skin mounted with a layer of Xinnaxing ointment (2 mm in thickness). After eschar removal, the burn wound was covered with the prepared porcine skin, sutured and fixed with small holes at the lower site for drainage. The growth of autogenous granule skin was then observed and the criteria for therapeutic effect evaluation drafted. Results The layer of Xinnaxing ointment on the the porcine skin improved the adhesion of the autogenous small skin grafts, therefore full use could be made of the donor skin source. In the 15 patients receiving this treatment, the graft-covered area was (12.3±3.5) % that of the wound, with the donor-recipient area ratio of 1: (11.0±2.7) and subsequent healing time of 27.5±5.5 d. Primary healing was achieved in 9 cases, and secondary healing in 6, demonstrating similar clinical effect to that of allo-skin grafting. Conclusion The method is easy and economic, which saves autogenous skin source and produces satisfactory clinical effect.更多还原