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89Sr内照射联合博宁治疗转移性骨痛

Therapeutic effect of internal 89Sr radiotherapy combined with bonin for metastatic bone pain

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【作者】 章必成张庆杜光祖李欣高建飞

【Author】 ZHANG Bi Cheng 1, ZHANG Qing 2, DU Guang Zu 1, LI Xin 1, GAO Jian Fei 1 1Department of Oncology, Wuhan General Hospital, Guangzhou Military Command of Chinese PLA, Wuhan 430070, China, 2First Department of Internal Medicine, Shaanxi Tumor Hospital, Xian 710061, China

【机构】 广州军区武汉总医院肿瘤科陕西省肿瘤医院内一科广州军区武汉总医院肿瘤科 湖北武汉430070陕西西安710061湖北武汉430070湖北武汉430070

【摘要】 目的 :评价89Sr内照射联合博宁治疗转移性骨痛的疗效 .方法 :88例转移性骨痛患者分为 3组 ,分别为89Sr内照射组 (2 9例 )、博宁组 (39例 )和89Sr内照射 +博宁组 (2 0例 ) ,观察止痛效果和毒副反应 .结果 :89Sr内照射组、博宁组和89Sr内照射 +博宁组骨痛缓解的有效率分别为 72 .4 % ,6 9.2 %和 95 .0 % ,89Sr内照射 +博宁组与其他两组比较均有显著性差异 (P <0 .0 5 ) ;3组均无明显的毒副反应 .结论 :89Sr内照射联合博宁是目前治疗转移性骨痛的优选方案 .

【Abstract】 AIM: To evaluate the pain control effects of internal 89 Sr radiotherapy combined with Bonin for metastatic bone pain. METHODS: Eighty eight patients with metastatic bone pain were divided into 3 groups. 29 patients received only internal 89 Sr radiotherapy, 39 patients received only Bonin, and the other 20 patients received internal 89 Sr radiotherapy combined with Bonin. The pain control effects and side effects were observed respectively. RESULTS: Effective rates of pain control of the three groups were 72.4%, 69.2% and 95.0% respectively. The effective rate of the group received internal 89 Sr radiotherapy combined with Bonin was distinctly different from that of the other groups ( P <0.05). No obvious side effects were found among the three groups. CONCLUSION: Internal 89 Sr radiotherapy combined with bonin is the first choice in treating metastatic bone pain.

【关键词】 89Sr内照射博宁骨肿瘤/继发性
【Key words】 Srinternal radiotherapyboninbone neoplasms/secondary
  • 【文献出处】 第四军医大学学报 ,Journal of The Fourth Military Medical University , 编辑部邮箱 ,2003年14期
  • 【分类号】R730.5
  • 【被引频次】3
  • 【下载频次】41
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