【摘要】 目的　建立基底神经节区域的可视化模型。方法　采用大体标本冰冻薄层断面切片技术 ,将人脑从冠状位、矢状位和轴位三个方位进行 0 43mm的薄层连续切片 ,以连合间径线的中点为原点建立空间坐标 ,对基底神经节核团断面的中心点坐标进行定位测量 ;在SGI工作站上 ,对首例中国数字化可视人体数据集中基底神经节及其周围的重要结构进行计算机三维重建。结果　尾状核头靶心坐标 (X ,Y ,Z)分别为 10 5 1± 1 67,2 3 80± 1 69,7 69± 1 46;苍白球内侧部靶心坐标为 18 3 0± 1 88,5 45± 1 3 5 ,0 88± 1 94;苍白球外侧部靶心坐标为 2 0 95± 1 79,7 62± 1 78,4 5 0± 1 40。对基底神经节的尾状核、壳核、苍白球以及周围的丘脑、丘脑底核、视神经等结构进行了可视化三维重建。重建的三维图像比较清楚地显示了基底神经节诸核团及其周围结构的空间形态和毗邻关系 ,并能方便地与断面形态相互参照。结论　基底神经节的可视化研究对于该区域疾病的影像学诊断和神经外科手术尤其是立体定向手术治疗具有重要的意义更多还原

【Abstract】 Objective To establish the visible model of the basal ganglia area Methods Brain serial thin cross sections of 0 43 mm were made from coronal, sagital and horizontal directions by cryomicrotome The midpoint coordinates of the basal ganglia nucleus on the cross section were measured in the coordinate system that was established on the midpoint of intercomissural distance An SGI workstation was employed to reconstruct three dimensional structures of the basal ganglia nucleus and some important surrounding structures based on the dataset from the first Chinese visible human Results The target coordinates of the caudate nucleus (X, Y, Z) were 10 51±1 67, 23 80±1 69 and 7 69±1 46; the internal globus pallidus 18 30±1 88,5 45±1 35 and 0 88±1 94; the external globus pallidus 20 95±1 79, 7 62±1 78 and 4 50±1 40, respectively The shapes, locations and adjacent relations of the basal ganglia were displayed clearly from computerized three dimensional reconstruction, which could be the cross reference of the cross sections expediently Conclusion The visualization of the basal ganglia can provide some guidance for the imaging diagnosis and the functional neurosurgery around this area更多还原