【摘要】 目的:用小鼠进行急性毒性实验,观察大理白族地区草鱼胆的毒性作用,计算LD₅₀,为实验研究和临床诊断提供依据;方法:给实验小鼠灌胃,观察小鼠不同时间的各种表现;采用改良Karder法计算草鱼胆半数致死量;结果:低剂量组动物灌胃后未见明显变化,其余各组均出现临床症状;草鱼胆的半数致死量(LD₅₀)为6.03ml·kg^-1。结论:大理地区草鱼胆汁有毒,一定量的草鱼胆汁可使小鼠发生中毒致死。更多还原

【Abstract】 Objective: The acute toxicity test in the mice was undertaken to provide evidence for study and clinic. Methods: all After grass carp bile was given by gavel, the manifestations were observed and LD50 of GCB was calculated by Karber method. Results: No significant changes were observed in the mice in the lowest concentration group, but Some of the animals appear clinic symptoms in the other groups; GCB, s LD50 is 6.03 ml·kg-1. Conclusions: GCB have toxic and can make mice died.更多还原