【摘要】 目的　探讨腹膜透析 (PD)治疗急性重症胰腺炎 (SAP)的可行性、疗效及机理。方法　 2 5例SAP患者随机分为腹膜透析组 (PD组 )和非腹膜透析组 (NPD组 ) ,PD组运用腹膜透析技术对 13例SAP患者进行腹膜透析治疗 ,NPD组运用常规治疗。比较两组间的疗效及局部和全身表现。结果　PD组及NPD组腹痛消失和腹胀缓解时间为 ( 16 5 1± 6 2 3 )hvs ( 82 0 6± 40 0 2 )h和 ( 2 4 91± 5 42 )hvs ( 5 9 45± 2 8 0 8)h ;住院天数和医疗费用为 ( 3 0 90± 2 1 73 )dvs ( 61 74± 16 88)d和 ( 4 73± 1 77)万元vs ( 9 16± 1 90 )万元 ;第 7d胰腺CT积分和APACHEII积分为 ( 4 96± 1 5 3 )分vs ( 7 3 7± 0 2 8)分和 ( 4 3 5± 1 75 )分vs ( 7 84± 2 5 9)分。两组比较PD组明显优于NPD组 (均P <0 0 5 )。结论　PD对早期SAP疗效显著 ,且方法简单、快捷、创伤小、并发症少 ,值得进一步推广应用和研究。更多还原

【Abstract】 Objective To inerstigate the feasibitity,the effects and the therapy of peritoneal dialysis(PD) on severe acute pancreatitis(SAP).Methods 26 cases of SAP were divided randomly into PD group and non-PD group (NPD).In PD group,13 patients of SAP were treated with PD,but NPD group were treated with routine therapy.The local,systemic manifestation were compared between two groups.Results In the PD and NPD group,the duration for disappearance of abdominal pain and tenderness,and amelioration for abdominal distension were (16 51±6 23)h vs (82 06±49 02)h and (24 91±5 42)h vs (59 45±28 08)h;The average hospital stay and cost of therapy were(30 90±21 73)d vs (61 74±16 88)d and (47300±17700) vs (91600±19000) RMB;CT scores and APACHE II scores at 7th day were(4 96±1 53) vs (7 37±0 28) and (4 35±1 75) vs (7 84±2 59).So that,superiority of the PD group to NPD group(P<0 05).Conclusions The PD method is easy,quick,small trauma,few complicated and effective in patients with early SAP,and will be of great value in wide-ranging application and further study.更多还原