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早产儿脑性瘫痪婴儿期症状临床流行病学研究

Epidemiologic Study of Infancy Symptoms of Cerebral Palsy in Premature Birth Children

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【作者】 王太梅李松赵凤临洪世欣林庆

【Author】 Tai Mei WANG, Song LI, Feng Lin ZHAO, Shi Xin HONG, Qing LIN. Department of Pediatrics, Third Hospital of Peking University, Beijing 100083, China

【机构】 北京大学第三医院儿科北京大学生育健康研究所北京大学第一医院儿科 北京100083北京100083北京100029

【摘要】 目的 了解小儿脑性瘫痪婴儿期症状 ,为儿科医生、儿保医生提供脑瘫的早期筛查、早期诊断线索。方法 对江苏省 7县市 1~ 6岁 4 16 7例早产儿脑瘫患病率、脑瘫婴儿期症状进行调查 ,由受过统一培训的儿科医生、儿保医生完成。结果 早产儿脑瘫患病率为 32 .9‰ ,胎龄小于 32周的早产儿脑瘫患病率为 34~ 37周早产儿的 3.6倍。脑瘫症状婴儿期的检出率在 30 %~ 6 2 %之间 ,特异度在 99.4 %以上 ,准确度在 97.2 %以上。阳性预测值在 80 %以上 ,阴性预测值在 97.5 %以上。结论 脑瘫婴儿期症状为早产儿脑瘫的早期诊断提供了依据 ,适用于脑瘫的早期筛查和早期诊断。

【Abstract】 Objective To study the infancy symptoms of premature birth children with cerebral palsy so as to provide a criterion for early screening and diagnosis of cerebral palsy. Methods The incidence of cerebral palsy and its infancy symptoms were investigated in 4 167 pre term birth children ranging from 1-6 years old from 7 counties/cities of Jiangsu Province. Pediatricians and health care doctors finished the investigation. Results The average incidence of cerebral palsy in pre term birth children was 32.9‰ . The incidence of cerebral palsy in pre term birth children with the gestational age of less than 32 weeks was 3.6 times as much as that in ones with the gestational age of 34-37 weeks. The positive rate of infancy symptoms of cerebral palsy was 30%-62%, with the specificity over 99.4% and veracity over 97.2% . The positive expected value was over 80%, and negative one was over 97.5% . Conclusions The infancy symptoms of cerebral palsy can be used for early screening and diagnosis for cerebral palsy in premature birth children.

【关键词】 脑性瘫痪症状早产儿
【Key words】 Cerebral palsySymptomPremature birth child
【基金】 国家医学科技攻关计划 (No .96-90 4-0 6-0 3 )
  • 【文献出处】 中国当代儿科杂志 ,The Chinese Journal of Contemporary Pediatrics , 编辑部邮箱 ,2003年04期
  • 【分类号】R742.3
  • 【被引频次】19
  • 【下载频次】177
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