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三叉神经支配对面瘫后肌球蛋白重链亚型的影响
Effect of trigeminus nerves innervation on the phenotype of MHC after facial paralysis
【摘要】 目的 :探讨三叉神经对失神经支配后面部上唇提肌肌球蛋白重链 (MHC)各亚型变化的影响。方法 :采用组织化学、SDS PAGE凝胶电泳以及电生理等方法观察上唇提肌形态学、电刺激收缩阈值、最大收缩力以及MHC各亚型的变化。结果 :三叉神经可以明显减轻面肌MHC各亚型去神经后的蛋白降解 ,维持肌纤维的兴奋阈值 ,保持肌纤维的最大收缩力。结论 :肌肉失神经支配后 ,感觉神经可以减轻MHC各亚型的蛋白降解 ,临床修复运动神经时应尽可能同时修复感觉神经
【Abstract】 Objective:To discuss the effect of trigeminus nerves on the phenotype of MHC after facial paralysis; Methods:The morphologic changes were observed by histochemical methods 、the phenotype of MHC by SDS PAGE 、the tension of contraction and the threshold value of electrical stimulation by electrical physiological methods; Results: trigeminus nerves could delay the decomposing of MHC, maintain the tension of contraction and the threshold value of electrical stimulation; Conclusion: Sensory nerves could delay the muscular atrophy ,and should be repaired when we repair motor nerves.
【Key words】 Trigeminal nerve; Facial paralysis; Myosin heavy chains; Denervation;
- 【文献出处】 北京大学学报(医学版) ,Journal of Peking University(Health Sciences) , 编辑部邮箱 ,2003年05期
- 【分类号】R745.12
- 【被引频次】2
- 【下载频次】64