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7种席夫碱对Zn2+的现场配位吸收光谱和99mTc现场配位法标记
ABSORPTIVE SPECTRAL STUDY ON COMPLEXING Zn2+ AND STUDY ON 99mTc LABELING OF THE IN SITU COORDINATION OF SEVEN SCHIFF BASES
【摘要】 通过电子吸收光谱研究了 7种水杨醛氨基酸席夫碱配体与Zn2 +离子在水溶液中现场配位的浓度下限、pH下限和配合的物稳定存在时间 .初步探索了在生理盐水中 7种水杨醛氨基酸席夫碱的99mTc现场标记 .实验结果初步揭示出现场配位法具有标记放射性金属核素的潜力
【Abstract】 The in situ coordination of seven salicylaldehyde amino acid Schiff bases in water is investigated. The minimum concentration and pH for coordinating to Zn 2+ and the existing time of the complexes are obtained through the measurement of absorption spectra. And the labeling of 99m Tc is tentatively performed, which indicates the potential of labeling radionuclides by means of the in situ coordination for radiopharmaceutical studies.
【关键词】 水杨醛氨基酸席夫碱;
Zn2+;
现场配位;
99mTc标记;
【Key words】 salicylaldehyde amino acid Schiff bases; Zn 2+; in situ coordination; 99m Tc labeling;
【Key words】 salicylaldehyde amino acid Schiff bases; Zn 2+; in situ coordination; 99m Tc labeling;
【基金】 国家自然科学基金资助项目 ( 2 97310 2 0 )
- 【文献出处】 北京师范大学学报(自然科学版) ,Journal of Beijing Normal University(Natural Science) , 编辑部邮箱 ,2003年06期
- 【分类号】O657.3
- 【被引频次】5
- 【下载频次】153