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火麻仁提取液对D半乳糖致衰模型小鼠学习记忆及代谢产物的影响
EFFECTS OF EXTRACTS OF FRUCTUS CANNABIS ON LEARNING AND MEMORY CAPACITY AND RELATED SUBSTANCES OF SENILE MICE INDUCED BY D-GALACTOSE
【摘要】 以D 半乳糖致衰小鼠为研究对象 ,灌服火麻仁提取液 6 0d ,测定对小鼠学习记忆能力、免疫器官质量和脂质过氧化的影响 .结果发现 ,火麻仁提取液 (2 0 g·kg- 1)对小鼠学习记忆有一定的改善作用 ,能显著增加致衰小鼠的脾指数 (P <0 .0 0 1) ,并且显著降低脑组织中丙二醛的质量摩尔浓度 (P <0 .0 5 ) .
【Abstract】 The extracts of Fructus cannabis (ig,60 d)could improve the learning and memory capacity of the subacute senile mouse models induced by the injection of D galactose subcutaneously. At the same time, it not only significantly increases index of spleen( P <0 001),but also lessens the level of malondialdehyde in brain of mice( P <0.05).
【关键词】 火麻仁;
致衰模型小鼠;
学习记忆;
脾指数;
过氧化脂质;
【Key words】 Fructus cannabis; senile mouse models; learning and memory; index of spleen; malondialdehyde;
【Key words】 Fructus cannabis; senile mouse models; learning and memory; index of spleen; malondialdehyde;
【基金】 国家自然科学基金资助项目 (39930 0 6 0 )
- 【文献出处】 北京师范大学学报(自然科学版) ,Journal of Beijing Normal University(Natural Science) , 编辑部邮箱 ,2003年03期
- 【分类号】R285.5
- 【被引频次】33
- 【下载频次】441