【摘要】 目的 :探讨五杞胶囊对小鼠急性肝损伤的保护作用。方法 :以四氯化碳、D-氨基半乳糖及醋氨酚诱导小鼠急性肝损伤模型 ,观察五杞胶囊的保肝作用。结果 :五杞胶囊 6、1 2 g· kg-1 (生药 )给小鼠连续灌胃 5 d,可明显对抗急性肝损伤模型小鼠血清 ALT及 AST的活力升高 ,并减轻小鼠肝脏坏死性病理改变。结论 :五杞胶囊具有保肝降酶作用 ,可能与其含有抗氧化作用的三种植物粗多糖及五味子乙素等有效成分有关。更多还原

【Abstract】 Objective:To observe protective effect of WUQI Capsule on acute hepatic injury. Methods:The models were induced by CCl 4,D Gal and acetaminophen. Results:WUQI Capsule (6 and 12 g·kg -1 ,ig×5 d) could significantly reduce the activity of ALT and AST in serum and lighten putrescence pathological change of liver in mice with acute hepatic injury.Conclusion:WUQI Capsule has protective effect on hepatic injury and depresses serum enzyme activities.更多还原