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金黄色葡萄球菌耐药性的研究

Study on the Drug Resistance of SA

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【作者】 何一中夏瑾

【Author】 He Yizhong, Xia Jin Zhejiang College of TCM , Hangzhou ( 310053 )

【机构】 浙江中医学院浙江中医学院 杭州 310053杭州 310053

【摘要】 目的:监测金黄色葡萄球菌(SA)的耐药状况,为临床治疗SA感染提供依据。方法:对浙江省中医院2001年6月至2002年5月临床分离出的122例金黄色葡萄球菌进行药敏试验和临床资料分析。结果:临床分离的葡萄球菌在病区、标本分布方面以重症监护病房和痰标本多见。耐苯唑西林金黄色葡萄球菌(MRSA)占70.5%(86/122);苯唑西林敏感金黄色葡萄球菌(MSSA)占29.5%(36/122)。耐万古霉素金黄色葡萄球菌占3.3%(4/122)。结论:耐苯唑西林的金黄色葡萄球菌表现为多重耐药性,且对12种抗生素的耐药率明显高于苯唑西林敏感的葡萄球菌,P<0.01。发现4株耐万古霉素的金黄色葡萄球菌。

【Abstract】 Objective: In order to control the nosocomial infections caused by Staphylococci aureus(SA) , the antibiotic resistance status of SA was investigated. Method: 122 strains of SA isolated clinically in Zhejaing Traditional Chinese Medical Hospital from Jun 2001 to May 2002 were tested for their drug-resistance, and the related clinical data were also analyzed. Results : SA isolated clinically was distributed more often in ICU than in other departments, more often in sputum than in other kinds of specimens. The percentages of methicillin-resistant Staphylococcus aureus ( MRSA) , of methicillin-sensitive Staphylococcus aureus (MSSA) , and of vancomycin-resistant Staphylococcus aureus were 70.5% (86/122) , 29.5% (36/122) and 3.3% (4/122) respectively. Conclusion: MRSA showed multiple resistance to antibiotics, the drug-resistant rate to 12 kinds of antibiotics was statistically and significantly higher than that of MSSA. 4 strains were found to be resistant to Vancomycin.

【关键词】 金黄色葡萄球菌MRSA耐药性
【Key words】 Staphylococci aureus(SA)MRSAdrug resistance
  • 【文献出处】 浙江中医学院学报 ,Journal of Zhejiang College of Tcm , 编辑部邮箱 ,2003年06期
  • 【分类号】R378
  • 【被引频次】3
  • 【下载频次】145
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