【摘要】 目的 :观察乙肝Ⅲ号合近红外信息辐照治疗乙型肝炎肝纤维化的疗效。方法 :选择乙型肝炎肝纤维化住院病人 2 34例 ,分为乙肝Ⅲ号治疗组 (76例 )、近红外信息辐照组 (73例 )和联合治疗组(85例 )。在基础治疗 (包括甘利欣 ,复方丹参液等 )上采用单纯的中药外敷、肝病治疗仪近红外信息辐照以及两者联合治疗等三种不同方法 ,观察各组患者临床症状、体征、肝功能以及相关指标如PGA、肝纤三项 (透明质酸 (HA)、层黏蛋白 (LN)、CⅣ型胶原 (CⅣ ) )、肝血流的变化。结果 :3组皆能改善临床症状 ,但以联合治疗组为著 ;3组肝功能复常比较 ,差异有显著性 ,但组间比较 ,差异无显著性 ;在改善PGA、肝纤三项和肝血流量方面 ,联合治疗组优于乙肝Ⅲ号治疗组和近红外信息辐照组。结论 :乙肝Ⅲ号合近红外信息辐照对乙型肝炎肝纤维化有一定的治疗作用 ,且较单一方法疗效明显。更多还原

【Abstract】 To observe the efficacy of Yigan Sanhao (YGSH), a traditional Chinese prescription for hepatitis B, combined with radiation of near infrared message by instrument of liver disease (DSG ⅠILD) in treatment of liver fibrosis due to hepatitis B. Method: Two hundreds and thirty four inpatients of liver fibrosis due to hepatitis B were divided into YGSH treated group (n=76),radiation of near infrared message treated group (n=73) and combined treatment group (n=85).On the basis of general treatment including drugs such as Diammonii Glycyrrhizinatis Injection and Danshen Compound Injection, patients were treated with external application of YGSH, radiation of infrared message by DSG-ⅠILD and combined treatment of YGSH and DSG ⅠILD, respectively. The clinical symptoms, syndromes, liver function, PGA, 3 indexes of liver fibrosis (hyaluronic acid, laminin and collagen Ⅳ) and the blood stream capacity of liver were observed. The clinical symptoms and signs of three groups were all improved, and the combined treatment is superior to the other two treatments in improving the clinical symptoms. After treatment, the liver function of three groups all recovered, but there was no significant difference among three groups.The combined treatment was superior to the other two treatments in improving PGA, 3 indexes of liver fibrosis and blood stream capacity of liver. Conclusion: The combined treatment of YGSH and DSG ⅠILD could effectively treat liver fibrosis due to hepatitis B,and its effects are superior to those of YGSH or DSG ⅠILD alone.更多还原