【摘要】 目的　调查大别山区肾综合征出血热微小疫源地演化及流行病学意义。方法　根据地理、地貌选择岳西县境内妙道山和菖蒲 2个调查点 (A点和B点 ) ,进行健康人群隐性感染调查 ,并用夹夜法调查小型兽类密度。采集捕获动物肺、血标本 ,检测汉坦病毒感染情况。结果　健康人群隐性感染率 2 .78% (2 /72 ) ;野外A点社鼠为优势鼠种 ,占夹捕小型兽类种类构成的 4 8.6 5 % (36 /74 ) ,捕获小型兽类总密度为 10 .6 2 % (74 /6 97) ,汉坦病毒 (HV)感染率为 12 .16 % (11/74 ) ,其中 10只为社鼠 ;野外B点社鼠构成比为 2 1.74 % (5 /2 3) ,小型兽类密度为 4 .31% (2 3/5 34) ,HV感染率为 8.70 % (2 /2 3) ,2只均为社鼠。结论　社鼠不仅是高山林区的主要宿主动物 ,而且是HFRS的主要传染源 ;肾综合征出血热微小疫源地已经强化。更多还原

【Abstract】 Objective To investigate evolution of foci epidemic areas and signification of epidemiology of HFRS in Dabie mountain. Methods Specific antibodies were detected for estimating recessive infection level of natural population and the density of small animals were studied in A and B spot selected by geographical and geomorphic features in Yuexi county. Hantan virus (HV) was detected from blood and lung samples of captured animals. Results The recessive infection rate was 2.78%(2/72) in natural population. In A spot of field, the dominant mice were Rattus confucianus that occupied 48.65%(36/74) of the captured animals, the total density of the captured animals was 10.62%(74/697), the infective rate of HV was 12.16%(11/74). In B spot of field, Rattus confucianus occupied 21.74%(5/23) of the captured animals, the total density was 4.31%(23/534), the infective rate was 8.70%. Conclusions Rattus confucianus was main host animal and principal infective source.The intensity of the foci epidemic areas of HFRS had been enhanced in Dabie mountain.更多还原